One-glance verdict
$148.99 our estimate vs market $64.73
Wall Street consensus: $91.42 (-38.6% lower than our fair-value estimate)
57% below our estimate, below the bear case
Fundamentals snapshot
BMRN · NMS · Healthcare · Biotechnology
Current price
$64.73
52-week range
$49.26 - $70.98
Market cap
$12.53B
One-glance verdict
Wall Street consensus: $91.42 (-38.6% lower than our fair-value estimate)
57% below our estimate, below the bear case
Balance sheet
Net debt $3.33B. Interest coverage shows how many times profit covers the interest bill.
What stands out
What this company does
BioMarin is a drug company that focuses on creating treatments for rare and life-threatening genetic conditions that often have no other options. It makes its money by selling a small number of these highly specialized drugs, like Voxzogo for a form of dwarfism, which allows it to face less competition but also makes its financial health dependent on the success of just a few products.
BioMarin was founded in 1997 with a specific focus on developing treatments for rare genetic diseases that other pharmaceutical companies often overlook. A key turning point was the approval of its first drug, Aldurazyme, in 2003, which established its expertise in enzyme replacement therapies (a way to replace a missing or deficient enzyme in the body to treat a disease). Over the years, the company has grown by acquiring other companies and expanding its pipeline (the set of drugs a company is developing) of treatments for various rare conditions. This strategy has made it a significant player in the orphan drug market, which are medicines for rare diseases.
Think of BioMarin as a company that creates highly specialized medicines for people born with rare genetic conditions that can be life-threatening. These aren't everyday drugs like aspirin; they are complex treatments for small groups of patients around the world. The company handles everything from discovering and developing these drugs to getting them approved by regulators and selling them to hospitals and specialty pharmacies. Their core focus is on enzyme replacement therapies and other genetic-based treatments that address the root cause of these diseases.
This is BioMarin's foundational and largest business area, making up a significant portion of its revenue. It includes a portfolio of drugs that replace missing or non-functioning enzymes in patients with rare metabolic disorders, such as various types of mucopolysaccharidosis (MPS) and phenylketonuria (PKU). Hospitals and specialty pharmacies purchase these therapies, which are often administered for a patient's entire life. Products in this group include Vimizim, Naglazyme, and Palynziq, which are crucial for the company's steady cash flow (the amount of cash a company generates).
This is a newer but rapidly growing part of BioMarin's business, centered around its product Voxzogo. Voxzogo is a treatment for achondroplasia, the most common form of dwarfism, and represents a significant growth area for the company. Unlike the enzyme therapies, this product targets a skeletal growth disorder. The customers are still specialized physicians and hospitals who treat children with this condition, and this segment is a key part of management's strategy for future growth.
This segment represents BioMarin's venture into gene therapy, a cutting-edge approach to treating genetic diseases. Roctavian is a one-time treatment for severe hemophilia A, a rare bleeding disorder. While technologically advanced, this business is smaller and more focused, with sales concentrated in the U.S., Germany, and Italy where reimbursement (the process by which insurance companies and governments pay for healthcare services) has been established. Recently, the company has decided to explore options to divest (sell off) this part of the business to focus on its other core areas.
Management's current strategy is to focus on and grow its core Enzyme Therapies and Skeletal Conditions businesses. They are aiming to expand the use of their existing drugs, like Voxzogo, for other related conditions and to bring new drugs in their pipeline to market. The company is also focused on improving its profitability by implementing a significant cost-saving program. A key part of their strategy involves divesting Roctavian to sharpen their focus on what they see as their most promising growth areas.
Price history
Earnings history
Click any quarter to read the call summary and what the numbers say.
Is it cheap or expensive?
Wall Street consensus is the average analyst price target: $91.42 (-38.6% lower than our fair-value estimate).
Our most-likely fair value is $148.99 a share — about 130.2% above today's price of $64.73, so the stock currently looks cheap (undervalued).
Is it drowning in debt?
Net debt $3.3B. Interest coverage 37.6x.
BioMarin Pharmaceutical Inc.'s profit covers its interest bill about 37.6 times over. which is stronger than most peers shown here and 1 peers sit below 1x, which is the danger zone where profit does not fully cover the interest bill.
Total debt $4.20B Interest coverage 37.57x This is the baseline the peer rows are being compared against.
Total debt $1.98B Interest coverage 342.44x +811% vs BMRN Carries about 9.1x more debt cushion than BMRN.
Total debt $1.06B Interest coverage -17.25x -100% vs BMRN This peer has almost no interest-payment cushion compared with BMRN.
Total debt $2.99B Interest coverage 1.99x -95% vs BMRN Carries about 18.9x less debt cushion than BMRN.
Total debt $461.60M Interest coverage 5.03x -87% vs BMRN Carries about 7.5x less debt cushion than BMRN.
Total debt $38.27M Interest coverage 553.04x +1,372% vs BMRN Carries about 14.7x more debt cushion than BMRN.
What you should know
The numbers
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Valuation
Profitability
Health
Growth
Cash flow
Dividend
Metric explainer
Debt comparison
What you should know